Subject Code: CY5L006 Subject Name: Principles of Organometallic and Bioinorganic Chemistry L-T-P: 3-1-0 Credit: 4
Prerequisite(s): Nil
Organometallic chemistry: Bonding models in sigma and pi-complexes. 18-electron formalism and isolobal principle.Basic concepts guiding the synthesis and stability of Li, Mg, B, Si organometallic compounds. Wades/Mingos/Jemmis rule. Basic concepts guiding the synthesis and stability of transition metal alkyls, carbonyls, alkenes, alkynes, arenes, allyls, carbenes, and metallocenes. Basic organometallic reactions: oxidative-addition, reductive elimination, transmetallation, insertion, nucleophilic attach on coordinated ligand. Typical examples of fluxional organometallics. Metal-metal bonding and meta clusters. Bioinorganic Chemistry: The biochemistry of Fe, Cu, Co and Cu. Hemoglobin, Hemocyanin, Ferredoxin, Cytochromes, Carbonic anhydrase, Vitamin B12. Dioxygen binding, Electron transfer, Alkylation reactions.

Text/ Reference Books:
  1.  Huheey J. E.; Keiter E. and Keiter R. Inorganic Chemistry, Harper Collins College.
  2. Crabtree R. H. The Organometallic Chemistry of the Transition Metals, Wiley.
  3. Lippard and Bartini Bioinorganic Chemistry.
  4. Reedijk J., Bioinorganic Catalysis, Marcel Dekker.
  5. Collman J. P.; Finke R. G. and Norton J. R. Principles & Applications of Organo-transition Metal Chemistry, University Science Books